Just three months since Wasps sealed their fourth league title in six years, England's top players are ready for another gruelling and thrilling Guinness Premiership campaign.
But this year, things are going to be slightly different.
The new deal between the clubs and the Rugby Football Union will give England exclusive access to elite players around the autumn Tests and Six Nations Championship, meaning some will miss up to nine Premiership games.
Meanwhile referees, coaches, players and fans have to get to grips with the Experimental Law Variations being trialled in the northern hemisphere for the first time this season.
To add extra spice, there is also the battle for places on next summer's British and Irish Lions tour to South Africa.
So how will your side fare this season? Who is destined for the play-offs and who will end up in a relegation scrap? We assess the prospects for all 12 teams, and welcome your views on 606.
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