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Before the latest round of Premier League fixtures, here is all the key injury news alongside essential Fantasy Premier League statistics.

The festivities kick off with Manchester United at home to Newcastle United on Boxing Day (20:00 GMT) - here is the full fixture list.

This article will be updated as Premier League managers give their weekly news conferences.

For more FPL help, don't miss our regular Friday Q&A from 15:30 BST live on the BBC Sport website, with one of our four experts answering your questions

Friday

Manchester United v Newcastle United (20:00 GMT)

Manchester United will be without captain Bruno Fernandes, who suffered a muscle injury in the defeat by Aston Villa at the weekend.

United will monitor Kobbie Mainoo, who was ruled out of that game after picking up a minor calf injury in training the day before.

Casemiro is available after suspension.

Newcastle are hoping goalkeeper Nick Pope will be fit enough to make the matchday squad after a groin injury.

The Magpies have been dealing with a defensive injury crisis but Tino Livramento's knee is not as serious as had been feared, while Sven Botman is making good progress after a back problem.

Players out: Newcastle - Osula, Botman, Trippier, Krafth, Burn, Livramento

Man Utd - Fernandes, Mbeumo, Amad Diallo, Mazraoui

Doubts: Newcastle - Pope

Doubts: Man Utd - Mainoo, Maguire, De Ligt

Key FPL notes:

  • Manchester United's Matheus Cunha (£8.0m) has produced two goals and one assist over the past three gameweeks. During this period, no player across any position has taken as many shots as the Brazilian (22).

  • Anthony Gordon (£7.3m) recorded his first assists of the season for Newcastle against Chelsea in gameweek 17. In the past four gameweeks, he has also successfully converted two penalties.

  • Nick Woltemade (£7.3m) scored twice against Chelsea on Saturday to take his Newcastle goal tally for the season to seven - only three FPL forwards have scored more.

Saturday

Nottingham Forest v Manchester City (12:30 GMT)

Nottingham Forest have no new reported injury problems.

Head coach Sean Dyche says Ola Aina is "progressing well" in his recovery from a hamstring injury but is still rebuilding his fitness.

Manchester City, who will have had a week off between matches, will assess their squad after they return from the three-day break manager Pep Guardiola has given them.

But Guardiola has warned his players that they will be weighed on their return: "The moment they arrive I want to see how they come back. They can eat but I want to control them.

"Imagine one player and now he's perfect but he will arrive with three kilos more. He will be in Manchester, he will not travel to Nottingham Forest."

Players out: Man City - Kovacic, Ait-Nouri, Marmoush

Nottingham Forest - Sangare, Boly, Aina, Wood, Yates

Doubts: Man City - Stones, Doku, Rodri, Bobb

Key FPL notes:

  • Nottingham Forest's Elliot Anderson (£5.3m) has produced 20 defensive contribution points this season, the most of any midfielder.

  • Only one defender has amassed more FPL points than the 36 of Manchester City's Ruben Dias (£5.7m) since gameweek 13.

  • Gameweek 17 was only the second time in six starts that Manchester City's Rayan Cherki (£6.6m) has blanked, yet he still created more chances (six) than any other player.

Arsenal v Brighton & Hove Albion (15:00 GMT)

Arsenal will need to see how their squad looks after their midweek EFL Cup quarter-final penalty shootout victory over Crystal Palace.

Kai Havertz, Cristian Mosquera, Ben White and Gabriel are among those currently sidelined.

Brighton forward Danny Welbeck has recovered from a back problem while Lewis Dunk and Diego Gomez are available again after suspension.

Defender Jan Paul van Hecke should be fit after a virus and Mats Wieffer is also expected to return.

Players out: Arsenal - Mosquera, White, Havertz, Gabriel, Dowman

Brighton - Tzimas, Webster, Baleba, March

Key FPL notes:

  • Arsenal's Bukayo Saka (£10.3m) has produced one goal and four assists over the past five gameweeks. During this period, only four midfielders have surpassed his 3.09 expected goal involvement (xGI) figure.

  • Declan Rice (£7.2m) recorded his sixth assist of the season for the Gunners in gameweek 17. Only three players have produced more, while only one has created more big chances (nine).

  • From gameweek 13 onwards, only one FPL defender (minimum four appearances) has a higher points per start average than Brighton's Maxim De Cuyper's (£4.3m) 7.3. The Dutchman has served up a goal, three clean sheets and five bonus points in that time.

Brentford v Bournemouth (15:00 GMT)

Brentford's on-loan winger Reiss Nelson could return after missing four matches with injury.

Josh Dasilva remains sidelined with a knee issue while Frank Onyeka and Dango Ouattara are at the Africa Cup of Nations.

Bournemouth head coach Andoni Iraola has reported no fresh injury problems.

Players out: Brentford - Dasilva, Onyeka, Ouattara, Carvalho, Milambo

Bournemouth - Gannon-Doak, Adams, Milosavljevic

Key FPL notes:

  • Since returning to the starting line-up in gameweek 16, Brentford's Keane Lewis-Potter (£4.8m) has produced 27 points, thanks to two goals, two clean sheets and three bonus points.

  • After going seven matches without an attacking return, Bournemouth's Antoine Semenyo (£7.7m) has now scored in back-to-back games.

  • Only one player had more shots than the six of Cherries' David Brooks (£5.0m) in gameweek 17.

Burnley v Everton (15:00 GMT)

Burnley defender Maxime Esteve is back in training after picking up a knock last week.

Axel Tuanzebe and Lyle Foster are both playing at the Africa Cup of Nations.

Everton manager David Moyes says his side have no fresh injury problems.

Jarrad Branthwaite and Seamus Coleman remain sidelined with hamstring issues.

Iliman Ndiaye and Idrissa Gueye are also at Afcon in the Senegal squad.

Players out: Burnley - Tuanzebe, Foster, Roberts, Mejbri, Beyer, Amdouni

Everton - Branthwaite, Coleman, Ndiaye, Gueye, Dewsbury-Hall

Doubts: Burnley - Esteve

Key FPL notes:

  • Zian Flemming (£5.3m) has scored five goals since gameweek nine. During this period, only two forwards have recorded more goals than the Burnley man, although all of his strikes have come away from home.

  • Everton's Michael Keane (£4.7m) is averaging 6.7 points per start across his past six matches, thanks to one goal, three clean sheets, eight defensive contribution points and five bonus.

  • Only four midfielders have created more chances than Jack Grealish's (6.5m) 30 for Everton this season, and only three have had more penalty box touches (88).

Liverpool v Wolves (15:00 GMT)

Liverpool will be without striker Alexander Isak, who has had surgery on a broken leg, but Florian Wirtz is fit again after coming off with cramp in the win over Tottenham.

Dominik Szoboszlai misses out after picking up his fifth yellow card last weekend.

Joe Gomez and Wataru Endo have been ruled out while Conor Bradley and Cody Gakpo are "50-50" according to head coach Arne Slot.

Wolves will be without captain Toti Gomes, who faces a few weeks out with hamstring issues.

However, Yerson Mosquera returns after suspension and Hugo Bueno is back in training and hoping to be fit.

Players out: Liverpool - Isak, Gomez, Endo, Salah, Szoboszlai, Leoni

Wolves - R Gomes, Toti, Bellegarde, Agbadou, Chirewa, Munetsi, Chiwome

Doubts: Liverpool - Bradley, Gakpo

Wolves - Bueno

Key FPL notes:

  • Hugo Ekitike (£8.9m) has scored five goals for Liverpool in the past three gameweeks. During this period, no forward has recorded as many goals, FPL points (36) or shots (12). He faces a Wolves side with the worst defence (37 goals conceded) in the division.

  • Florian Wirtz (£8.1m) has produced two assists, five bonus and two defensive contribution points in his past four matches for the Reds.

  • Tolu Arokodare (£5.4m) has been Wolves' highest-scoring player over the past three gameweeks, but has only produced nine points.

West Ham v Fulham (15:00 GMT)

West Ham are without Aaron Wan-Bissaka and El Hadji Malick Diouf, who are both at the Africa Cup of Nations.

Fulham are hopeful Harry Wilson will be fit despite limping off with a knee injury in the win over Nottingham Forest on Monday.

The Cottagers will be without Calvin Bassey, Samuel Chukwueze and Alex Iwobi, all of whom are at Afcon with Nigeria.

Rodrigo Muniz and Ryan Sessegnon remain sidelined with injury.

Players out: West Ham - Wan-Bissaka, Diouf

Fulham - Bassey, Chukwueze, Iwobi, Muniz, Sessegnon

Key FPL notes:

  • Jarrod Bowen's (£7.6m) blank for West Ham against Manchester City in gameweek 17 was his first in four matches. In that time, only three forwards have attempted more shots (12).

  • Only Marcos Senesi (£4.9m) has achieved more defensive contribution points than the 22 of Joachim Andersen (£4.6m). The defender has kept two clean sheets in the last six gameweeks and is the second-highest scoring player at Fulham (63).

  • Since gameweek 13, only two midfielders have amassed more FPL points than Harry Wilson's (£5.8m) 44. The Fulham player has produced three goals, four assists and seven bonus in that time.

Chelsea v Aston Villa (17:30 GMT)

Chelsea will assess striker Liam Delap, who has missed the past four matches with a shoulder injury.

Teenage winger Estevao is also being monitored after sitting out two matches with a muscle issue.

Aston Villa wide man Evann Guessand has left for the Africa Cup of Nations after receiving a late call-up from Ivory Coast.

Jadon Sancho is available again after being ineligible to face his parent club Manchester United.

Players out: Chelsea - Colwill, Lavia, Essugo, Mudryk

Players out: Aston Villa - Guessand, Barkley, Mings, Torres

Doubts: Chelsea - Delap, Estevao

Doubts: Aston Villa - Elliott

Key FPL notes:

  • Chelsea's Cole Palmer (£10.4m) has produced a goal and an assist in his past two matches and racked up 14 points in this fixture last season.

  • Chelsea's Trevoh Chalobah (£5.5m) is the highest-scoring defender in FPL with 94 points, having produced one goal, three clean sheets, six defensive contribution points and five bonus over the past six gameweeks.

  • Morgan Rogers (£7.2m) has racked up 15-pointers in three of the past six gameweeks. In that time, among midfielders, the Aston Villa man ranks top for goals scored (six), second for FPL points (56) and third for shots taken (19).

Sunday

Sunderland v Leeds United (14:00 GMT)

Sunderland are still without Luke O'Nien, who is serving a three-match ban.

Habib Diarra has now travelled to the Africa Cup of Nations, where he will join five other Black Cats players: Arthur Masuaku, Noah Sadiki, Reinildo, Chemsdine Talbi and Bertrand Traore.

This game comes too soon for Leeds midfielder Sean Longstaff, who has a calf injury.

Winger Daniel James is still out with a hamstring injury.

But Lucas Nmecha, who has missed three games with a hamstring problem, could return.

Players out: Sunderland - Diarra, O'Nien, Traore, Talbi, Reinildo, Sadiki, Masuaku, Alese

Leeds - James, Longstaff

Doubts: Leeds - Nmecha

Key FPL notes:

  • Sunderland's Robin Roefs (£4.8m) has kept back-to-back clean sheets to move on to six shut-outs for the season. He is the highest-scoring goalkeeper in FPL with 80 points but remains a differential, with an ownership of just under 10%.

  • In his past six home matches, Sunderland defender Dan Ballard (£4.7m) has produced 36 points for an average of just over seven points per appearance.

  • Dominic Calvert-Lewin (£5.8m) has scored six goals across the past five gameweeks. During this period, Erling Haaland (£15.1m) is the only forward to have returned more FPL points than the Leeds striker's 44 or had more than his seven big chances.

Crystal Palace v Tottenham Hotspur (16:30 GMT)

Crystal Palace will assess their squad after the midweek EFL Cup quarter-final penalty shootout defeat by Arsenal.

Ismaila Sarr is at the Africa Cup of Nations while Daichi Kamada, Cheick Doucoure and Daniel Munoz remain sidelined with injury.

Tottenham have no new injury problems but will be without Cristian Romero and Xavi Simons, who are both suspended.

Yves Bissouma and Papa Mate Sarr are both at Afcon.

Players out: Crystal Palace - Sarr, Kamada, Munoz, Doucoure

Tottenham - Romero, Simons, Maddison, Sarr, Bissouma, Udogie, Solanke, Kulusevski

Key FPL notes:

  • Crystal Palace's Marc Guehi (£5.3m) is the second-highest scoring defender in FPL (93). He has produced two goals, four assists and six clean sheets in total but has mustered only two shut-outs since gameweek 10 (against Burnley and Wolves).

  • Maxence Lacroix (£5.2m) is among the five best defenders in FPL. Seven clean sheets, two assists and 14 defensive contribution points have helped the Palace centre-back amass 82 points in total.

  • Only four forwards have produced more goals in the past seven gameweeks than Tottenham's Richarlison (£6.4m), with four.

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