Almost 350 of the world's top disabled athletes from 47 countries will be in Manchester for the Visa Paralympic World Cup in May.
This is the third year of the event which will run from 7-13 May at three venues in Manchester with wheelchair basketball, cycling, swimming and athletics all featuring on the schedule.
Among the highlights will be Dame Tanni Grey-Thompson's final race before she brings the curtain down on her illustrious career.
BBC Sport gives you the lowdown on what to expect from each event.
There will be live coverage from the Paralympic World Cup on Sunday 13 May on BBC Two from 1545-1745 BST.
WHEELCHAIR BASKETBALL
Pool Games: 7-8 May (0930-2200 each day)
Semi-Finals: 9 May (1000-1900)
Finals: 10 May (1000-1900)
Venue: Manchester Velodrome
The Great Britain men's team will face a difficult assignment as they bid to improve on the bronze medal they won last year.
New coach Murray Treseder will be at the helm for the first time as they take on his former side Australia, Paralympic champions Canada and the Netherlands.
GB will launch their campaign against Australia on Monday at 1530 and face Canada and the Netherlands on Tuesday before the semi-finals and finals.
The GB women's team, who finished second last year, take on Spain, Japan and France as they continue their preparations for the European Championships later this year.
CYCLING
Date: Friday 11 May
Time: 1300-1600
Venue: Manchester Velodrome
The Great Britain cycling team will be hoping to once again make a big impression on home soil in an event where they won seven gold medals and set five world records 12 months ago.
The team features Paralympic gold medallists Darren Kenny and tandem sprint pairing Aileen McGlynn and Ellen Hunter.
World champions Anthony Kappes and Barney Storey will be bidding for success in the men's tandem sprint against two strong Australian teams.
Paralympic swimming medallists Sarah Bailey and Jody Cundy, who have both made successful transitions to the velodrome, will also be in action.
SWIMMING
Date: Saturday 12 May
Heats: 1000-1200
Finals: 1500-1745
Venue: Manchester Aquatics Centre
The British Paralympic swimming team are in superb form after topping the medal table at last December's IPC World Swimming Championships in Durban.
Team GB came away with 24 golds, 14 silvers and 14 bronzes from South Africa and will be hoping to continue their good run.
The team features some experienced campaigners including Athens gold medallists Sascha Kindred, Dave Roberts, Nyree Lewis and Natalie Jones.
Talented British youngsters including Matt Whorwood, Emma Cattle and Jonathan Fox will make their Paralympic World Cup debuts.
They will be joined by some top-class international swimmers, including world champions Natalie du Toit from South Africa and Jessica Long of the USA.
ATHLETICS
Date: 13 May
Time: 1430-1750
Venue: Manchester Regional Arena
Dame Tanni Grey-Thompson will race for the final time when she lines up in the T53 200m.
London Marathon winners Dave Weir and Shelly Woods will be hoping to add to their recent successes when they take to the track.
Weir will race in the T54 200 and 400m while Woods is in action in the T54 400 and 800m.
Emerging talents Elizabeth Clegg, Katherine Deal and Ben Rushgrove will be joined by familiar faces such as Danny Crates, Stephen Miller and Graeme Ballard.
South African sprint star Oscar Pistorius will be bidding for a sprint double in the T44 100 and 200m
Pistorius recently became the first double amputee to run below 11 seconds for the 100m at the SA Disabled Championships.
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